Hypersensitivity reactions to human insulin analogs in insulin-naive patients: a systematic review

AS Bzowyckyj, AM Stahnke - Therapeutic Advances in …, 2018 - journals.sagepub.com
… manufacture insulin have remained the same (eg meta-cresol… changes indicative of a
severe insulin allergy. Glycemic … preservative meta-cresol and a report of cutaneous allergy to …

[HTML][HTML] Allergic and non-allergic skin reactions associated with growth hormone therapy: elucidation of causative agents

S Mehta, V Oza, R Potashner, P Zamora… - Journal of Pediatric …, 2018 - degruyter.com
… I HS reactions to m-cresol have been reported with insulin [20], [24]. To our knowledge, only
one case of m-cresol sensitivity … and chronic, plaque-stage psoriasis who developed acute

[HTML][HTML] Exogenous recombinant human insulin-induced severe hypersensitivity reaction precipitating hyperglycemic crisis: A clinical conundrum

KU Lijesh, RD Gupta, M SenthilRaja… - Journal of Family …, 2020 - journals.lww.com
skin biopsy showing evidence of insulin hypersensitivity. He was desensitized to insulin
according to Heinzerling et al. insulin … , latex, or cresol. Subcutaneous injections compared to …

[PDF][PDF] Clinical challenges with excipients in insulin formulations and role of concentrated insulin

KD Modi, PV Gadge, P Jain, S Pawar… - Int J Basic Clin …, 2019 - academia.edu
… and meta-cresol in adequate concentration are added in insulin … Drug intolerance reaction
to insulin therapy caused by … Skin-related complications of insulin therapy: epidemiology and …

[PDF][PDF] Insulin Allergy.

F Erdenen… - Istanbul Medical …, 2016 - cms.istanbulmedicaljournal.org
… can range from local reactions to severe anaphylaxis. Local … Sensitivity that starts with local
symptoms may be aggravated … A (+) skin reaction may be observed with cresol in saline. 1.5 …

Delayed-type Hypersensitivity Reaction to Glargine and Biphasic Isophane Human Insulin in a Filipino Patient with Type 2 Diabetes Mellitus: A Practical Approach to …

CSC Tan-Lim, AS de Peralta… - Acta Medica …, 2022 - actamedicaphilippina.upm.edu.ph
… This report illustrates a case of an insulin hypersensitivity reaction successfully diagnosed …
Severe adverse cutaneous reaction to insulin due to cresol sensitivity. Contact Dermatitis 2006…

Insulin Therapy:“When Saviour Turns Hostile”

DSMVH Nagarajappaa, SOSSM Srinivasc, R Palanya - 2022 - karger.com
… Additives in insulin preparations, such as protamine, zinc, and cresol, have been shown
to … Severe adverse cutaneous reaction to insulin due to cresol sensitivity. Contact Dermatitis. …

[HTML][HTML] Insulin Therapy:“When Saviour Turns Hostile”

D Soodhana Mohan, V Hebbal Nagarajappa… - Dubai Diabetes and …, 2022 - karger.com
… She had no known drug or food sensitivities. … Additives in insulin preparations, such as
protamine, zinc, and cresol, … Because the skin lesions in our patients were caused by the injection …

Insulin, not the preservative m-cresol, instigates loss of infusion site patency over extended durations of CSII in diabetic swine

MR Swinney, AL Cox, ED Hawkins, J Xue… - Journal of …, 2021 - Elsevier
… that they either severely over-dosed m-cresol, 27 evaluated … focusing on the dermal and
subcutaneous tissues, due to their … rat insulin kit recognizes human insulin with higher sensitivity

[PDF][PDF] The natural metabolite 4-cresol improves glucose homeostasis and enhances β-cell function

F Brial, F Alzaid, K Sonomura, Y Kamatani, K Meneyrol… - Cell Reports, 2020 - cell.com
… In vivo insulin sensitivity is not affected by 4-cresol. The … 4-cresol results in enhanced
insulin secretion, insulin content, … strate that chronic administration of a non-toxic dose of 4-cresol